Functional Categories

Gene Name

Copies

Hormones and cytokines

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growth hormone

385

prolactin

242

chorionic gonadotropin

40

proopiomelanocortin (POMC)

33

pro-galanin

8

cocaine and amphetamine regulated transcript CART(hCART)

7

TSH-beta

4

LH beta subunit

3

chorionic gonadotropin (hcg) beta subunit

2

endothelin 3

2

epithelin 1 and 2

2

growth hormone 20k

2

thyroid stimulating hormone

2

tumor necrosis factor

2

amyloid protein (AD-AP)

1

angiopoietin-2

1

growth factor FIGF

1

HE1 (a major secretory protein of the human epididymis )

1

kidney epidermal growth factor (EGF)

1

preprocortistatin (Cort)

1

preproenkephalin

1

glycoprotein, alpha-subunit

1

Receptors

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vasopressin activated calcium mobilizing receptor-like protein

3

novel protein produced by glioblastoma(heparin-binding growth factor receptor K-sam)

2

Somatostatin receptor subtype 3

2

beta-glucocorticoid receptor

1

D2 dopamine receptor

1

estrogen related receptor alpha (ESTRRA)

1

Frizzled-6 (recepter )

1

glucocorticoid receptor alpha-2

1

growth hormone-releasing hormone receptor

1

oestrogen receptor

1

purinergic receptor P2Y5

1

retinoid X receptor-gamma

1

TGF-betaIIR alpha(human transforming growth factor-beta type II receptor)

1

thyroid hormone receptor

1

tumor necrosis factor receptor 2 (TNFR2)

1

type 1 inositol 1,4,5-trisphosphate receptor

1

TEGT (testis enhanced gene transcript seven potential transmembrane domains)

1

Signal transduction

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GsGTP binding protein alpha subunit

42

thyroid hormone receptor coactivating protein

14

calmodulin

10

insulin induced protein 1 (INSIG1)

7

epidermal growth factor receptor substrate

4

HS1 binding protein HAX-1

4

LGN protein ( interaction with G alpha i2 )

4

Gps1 (GPS1)(suppress G-protein)

3

PIG-F (phosphatidyl-inositol-glycan classF)

3

protein tyrosine phosphatase receptor pi (PTPRP)

3

PtdIns 4-kinase

3

androgen receptor associated protein 24(ARA24)

2

cAMP-dependent protein kinase type I-alpha subunit

2

GTP-binding protein (rhoA)

2

HS1 protein

2

lipocortin

2

lipocortin II

2

NADP-regulated thyroid-hormone binding protein

2

protein tyrosine phosphatase (PTP-BAS, type 3)

2

protein tyrosine phosphatase delta

2

protein-tyrosine phosphatase (PTPase MEG2)

2

transactivator (jun-B)

2

14-3-3 epsilon

1

PIT1(transcription factor Pit-1) gene for pituitary specific POU-domain DNA binding factor

1

proto-oncogene (c-fos)

1

p300/CBP-associated factor

1

14-3-3 protein epsilon isoform

1

14.3.3 protein, a protein kinase regulator,

1

ataxia telangiectasia (ATM)(phosphatidylinositol 3-kinase homolog)

1

B-cell receptor associated protein (hBAP)

1

beta-subunit signal transducing proteins Gs/Gi

1

calcineurin A1

1

cAMP-dependent protein kinase regulatory subunit type I (PRKAR1A)

1

G protein alpha-olf subunit

1

G protein-coupled receptor kinase

1

GS3955(putative serine/threonine kinase expressed in human osteoblast)

1

GTP binding protein

1

guanylate cyclase

1

HPTP delta mRNA for protein tyrosine phosphatase delta

1

ICERE-1(inversely correlated with estrogen receptor expression)

1

LDL-receptor related protein

1

MAP kinase

1

OB-RGRP

1

phosphatase 2A

1

phosphatidylinositol synthase (PIS)

1

phosphodiesterase 3B

1

phospholipase D2

1

phosphorylase kinase alpha subunit

1

protein containing SH3 domain, SH3GL2

1

protein kinase C iota isoform (PRKCI)

1

protein kinase C-binding protein RACK7

1

protein kinase CK1

1

protein kinase inhibitor p58

1

protein kinase regulator

1

protein tyrosine kinase

1

protein tyrosine phosphatase

1

protein tyrosine phosphatase (PTPase)

1

protein tyrosine phosphatase (TEP1)

1

protein tyrosinephosphatase (ptp-IV1r)

1

putative serine/threonine proteinkinase

1

regulator of G protein signaling (RGS5)

1

Sel-1 like (Notch signaling pathway)

1

signal recognition particle (SRP54)

1

soluble guanylate cyclase small subunit

1

STE20-like kinase 3 (serine/threonine protein kinase family )

1

thyroid hormone receptor-associated protein complex component TRAP100

1

thyroid receptor interactor (TRIP7)

1

transducin beta-2 subunit

1

transforming growth factor-beta induced gene product (BIGH3)

1

Genes involved in secretion, transportation and metabolism of hormones

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secretogranin I (chromogranin B)

8

polypeptide 7B2

5

78 kDa gastrin-binding protein

3

17-beta-hydroxysteroid dehydrogenase

2

amyloid precursor protein-binding protein 1

2

Jk-recombination signal binding protein (RBPJK)

2

PC1/PC3

2

secretogranin II

2

11-beta-hydroxysteroid dehydrogenase (HSD11)

1

adenylyl cyclase-associated protein (CAP)

1

ER-60 protease

1

ERp28 protein (endoplasmic-reticulum-lumenal

1

insulin-like growth factor binding protein 5 (IGFBP5)

1

p1159vesicle docking protein p115

1

Rab11

1

signal recognition particle subunit

1

signal recognition particle subunit 9(SRP9)

1

catechol-O-methyltransferase

1

unclassified genes

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hbrm

2

S63912 ME2

1

putative ribulose-5-phosphate-epimerase

1

homologous to mouse P21

1

enigma protein

1

Efs2

1

E-MAP-115

1

dishevelled 3

1

Cks1 protein homologue

1

80K-L protein

1