Functional Categories

Gene Name

Hormones and cytokines

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Pro-melanin-concentrating hormone

vascular endothelial growth factor (VEGF(165))

c-sis/platelet-derived growth factor 2 (SIS/PDGF2)

Platelet-derived growth factor PDGF-A

Adenylate cyclase activating polypeptide 1

cocaine and amphetamine regulated transcript CART(hCART) ( a new anorectic peptide regulated by leptin)

Insulin-like growth factor 1

adrenomedullin

ALK-3 (members of the transforming growth factor-beta cytokine family,)

Angiotensinogen

basic fibroblast growth factor (bFGF) 22.5 kd, 21 kd and 18 kd protein

cholecystokinin (CCK)

Endothelin 3

lens epithelium-derived growth factor

Transforming growth factor, alpha

Receptors

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Fibroblast growth factor receptor 2

p40(a novel putative G protein-coupled receptor)

type 2 inositol 1,4,5-trisphosphate receptor

v-erbA related ear-2(hormone receptor)

Glutamate receptor, ionotropic, AMPA 2

platelet-derived growth factor receptor alpha (PDGFRA)

RAMP2( a receptor of calcitonin-gene-related peptide)

epidermal growth factor receptor (HER3)

homologue of the canine orphan receptor (RDC1)

leptin receptor short form (db)

putative endothelin receptor type B-like protein

TGF-betaIIR alpha

transmembrane receptor (ror1)

Signal transduction

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alpha subunit of GsGTP binding protein

calmodulin

calmodulin-I (CALM1)

14.3.3 protein, a protein kinase regulator

AMP-specific phosphodiesterase 8A (PDE8A)

Ca2+-dependent activator protein for secretion

Epidermal growth factor receptor pathway substrate 15

GTP-binding protein (RAB1)

myosin light chain kinase (MLCK)

phosphatidylinositol (4,5)bisphosphate 5-phosphatase homolog

protein kinase (JNK2)

serine/threonine protein kinase

small GTP-binding protein

adenylyl cyclase-associated protein (CAP)

CAMP-dependent protein kinase regulatory subunit type I

Gps1 (GPS1)(suppress G-protein)

LGN protein ( interaction with G alpha i2 )

major astrocytic phosphoprotein PEA-15

MAP kinase kinase 4 (MKK4)

NIPSNAP2 protein(a substrate for tyrosine kinases)

protein kinase inhibitor p58

protein tyrosine kinase t-Ror1 (Ror1)

protein tyrosine phosphatase

Protein tyrosine phosphatase, receptor type, alpha polypeptide

putative protein kinase C inhibitor (PKCI-1)

receptor tyrosine kinase DDR

tyrosine phosphatase (PRL-1)

3-phosphoinositide dependent protein kinase-1(PDK1)

68 kDa type I phosphatidylinositol-4-phosphate 5-kinase alpha

alpha endosulfine

alpha-subunit of Gi2 exon 9, a GTP-binding signal transduction protein

antisecretory factor-1

ataxia telangiectasia (ATM)(phosphatidylinositol 3-kinase homolog)

Ca2+-dependent activator protein

calmodulin-like, processed pseudogene

cAMP response element-binding protein (CRE-BP1)

epidermal growth factor receptor kinase substrate(Eps8)

eps8( Eps8, a substrate of receptor tyrosine kinases,) binding protein e3B1

G protein beta 5 subunit

G protein gamma-10 subunit

Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2

Guanine nucleotide binding protein (G protein), q polypeptide

inositol 1,3,4-trisphosphate 5/6-kinase

Inositol 1,4,5-trisphosphate 3-kinase B

inositol polyphosphate 4-phosphatase type II-alpha

Insulin-like growth factor binding protein 6

integrin binding protein Del-1 (Del1)

Jak2 kinase

OB-R gene related protein(OB-RGRP)

phosphatidylinositol 3-kinase catalytic subunit p110delta

phosphatidylinositol 3-kinase p110 beta isoform

PRKY protein ( represents a member of the cAMP-dependent serine threonine protein kinase gene family )

prolactin receptor-associated protein (PRA)

protein kinase (JNK1)

Protein kinase C, zeta

protein kinase inhibitor

Protein serine/threonine kinase stk2

Protein tyrosine phosphatase, receptor type, mu polypeptide

receptor protein-tyrosine kinase (HEK8)

receptor-related tyrosine kinase

regulator of G protein signaling 10

The regulator of G-protein signaling (RGS) proteins 5 (RGS5 )

thyroid receptor interactor (TRIP14)

thyroid receptor interactor (TRIP7)

tyrosine phosphatase

YSK1 ( a novel mammalian protein kinase )

Stat2

ZAKI-4(a novel thyroid hormone-responsive)

Genes involved in secretion, transportation and metabolism of hormones

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secretogranin II

Aplysia ras-related homolog 12

ras-like protein

ras-related GTP-binding protein

signal recognition particle subunit 9

Chromogranin B (secretogranin 1)

fungal sterol-C5-desaturase homolog

Steroidogenic acute regulatory protein

type II 3-beta hydroxysteroid dehydrogenase/ 5-delta - 4-delta isomerase

17-beta-hydroxysteroid dehydrogenase

cleavage signal 1 protein

ELP-1

Growth factor receptor-bound protein 2

RAB7 protein

Sec23A isoform( vesicles in the formation of Golgi elements)

sex hormone-binding globulin (SHBG)

signal transducing adaptor molecule STAM

sterol carrier protein-X/sterol carrier protein-2(SCP-X/SCP-2)

chromogranin A (CHGA)

cytochrome P-450 1

Cytochrome P450, subfamily XVII (steroid 17-alpha-hydroxylase)

ERp28 protein (endoplasmic-reticulum-lumenal protein )

GDP dissociation inhibitor beta ( rab GDI )

NRD2 convertase (a metalloendopeptidase of the

rab11a GTPase

Rac3 (RAC3)(a novel member of the Rho family)

ras GTPase-activating-like protein (IQGAP1)

Ras-like small GTPase RIBA mRNA

Signal recognition particle receptor

small GTP-binding protein, S10

TCB gene encoding cytosolic thyroid hormone-binding protein

VAMP-associated protein of 33 kDa (vesicle-associated membrane protein , VAP-33)

unclassified genes

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protein gene product (PGP) 9.5(neuroendocrine marker protein)

amyloid precursor protein

neuroendocrine-specific protein A (NSP)

amyloid precursor-like protein 1

APPH=amyloid precursor protein homolog

hbrm

COP9 homolog (HCOP9)

dishevelled 1 (DVL1)

HE1

senilin 1 (PS1; S182)